Research Associate I-III IN VIVO

WHAT WE DO:

Calidi Biotherapeutics is a clinical-stage immuno-oncology company with proprietary technology that is revolutionizing the utilization of oncolytic viruses through an allogeneic cell-based delivery system. Calidi Biotherapeutics is advancing this potent stem cell and oncolytic virus combination for use in multiple difficult-to-treat oncology indications. Our team is also developing a universal cell delivery system to protect, amplify and potentiate oncolytic viruses currently in development.

GENERAL PURPOSE OF JOB:

The IN VIVO Research Associate, performs research and/or development in collaboration with others for projects. Makes detailed observations, analyzes data and interprets results. Research involves the use of oncolytic viruses, tumor biopsies, murine and human cell lines, experimental cancer model tissues, and blood from cancer patients and healthy donors.

ESSENTIAL DUTIES AND RESPONSIBILITIES:

• Performs in vivo studies to evaluate efficacy in murine models
• Administers test substances by various routes (i.e., intratumoral, IP, IV, SC, PO, topical, etc.)
• Performs mouse necropsies, tissue harvest, and mouse blood collection via: cardiac puncture, submandibular, retro orbital etc.
• Models pre-clinical tumors
• Handles and doses animals (Intratumoral, IP, IV, PO, and SC), bleeding, necropsy and tissue harvest
• Performs in vivo imaging to monitor tumor growth (IVIS or equivalent)
• Manages and observe animals for general health and overall well-being
• Independently performs all methods and conducts all study types commonly employed by the team
• Maintains accurate experiment records in various internal databases and performs basic data analysis
• Adheres to good health and safety practices and compliance with applicable EH&S rules and participating in mandatory safety training programs
• Adheres to SOPs to ensure study integrity and quality
• Experience in qPCR, ELISA, immuno-oncology, TIL isolation, and flow cytometry is a plus
• Other duties as needed

EDUCATION and/or EXPERIENCE:

• 2+ years of experience animal laboratory setting
• Good organizational and documentation skills
• Dedication to working in a team-oriented environment to contribute to shared project
• Strong work ethic, self-motivation, and ability to multi-task in a fast-paced work environment
• Strong knowledge of MS Word, Outlook, PowerPoint, Excel.

MATHEMATICAL SKILLS:

• Ability to work with mathematical concepts such as calculation of dilutions and statistical analyses.
• Ability to apply concepts such as fractions, percentages, ratios, and proportions to practical situations.

REASONING ABILITY:

• Ability to define problems, collect data, establish facts, and draw valid conclusions.

LANGUAGE SKILLS:

• Excellent communication skills with ability to effectively communicate with other research teams
• Ability to read and understand technical procedures
• Ability to write protocols and reports
• Ability to effectively present data and respond to questions from co-workers

PHYSICAL DEMANDS:

The physical demands described here are representative of those that must be met by an employee to successfully perform the essential functions of this job. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.

Amount of Time

Weight lifted or force to be exerted:

Amount of Time

The PERKS:

• Monthly onsite meals, daily snacks and beverages
• Team building activities
• Competitive Total Rewards package (Medical, Dental, Vision, 401k Safe Harbor Match) offered to full-time employees

WORK LOCATION:

Calidi Biotherapeutics employment provides the opportunity to work in beautiful San Diego, California only minutes from the nearest beach.

EOE and Accommodation:

We value diversity and are proud to be an Equal Opportunity and Affirmative Action employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, protected veteran status, pregnancy, citizenship, marital status, gender expression, genetic information, political affiliation, or any other characteristic protected by law. Calidi Biotherapeutics provides reasonable accommodation in job application procedures for qualified individuals with disabilities and disabled veterans. If you need accommodation in connection with the recruiting process due to a disability, you may include this information in your cover letter. If you are selected to interview for a position, you may also request an accommodation with our team directly.

Notice to Agency and Search Firm Representatives

Calidi Biotherapeutics is not accepting unsolicited resumes from agencies and/or search firms for this job posting. Resumes submitted to any Calidi Biotherapeutics employee by a third-party agency and/or search firm without a valid written & signed search agreement, will become the sole property of Calidi Biotherapeutics. No fee will be paid if a candidate is hired for this position as a result of an unsolicited agency or search firm referral.

EMPLOYER’S RIGHTS:

This job description does not list all the duties of the job. You may be asked by supervisors or managers to perform other duties. You will be evaluated in part based upon your performance of the tasks listed in this job description.

The employer has the right to revise this job description at any time. The job description is not a contract for employment, and either you or the employer may terminate employment at any time, for any reason.